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Megestrol                                                 

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現行藥物外觀

中文名:麥格斯口服懸液劑 40 毫克/毫升

廠牌:晟德/台灣東洋

 

 

Product name
Megest
Dosage form
(40mg/ml,120ml)口服懸液
Indications
 
Administration & Dosage

PO

ADULT

1)Breast cancer, palliative treatment of advanced disease (recurrent, inoperable, or metastatic): 40 mg QID.

2)Cachexia associated with AIDS: initial, 800 mg/day; maintenance, 400 and 800 mg/day were found to be clinically effective.

3)Carcinoma of prostate, Advanced hormone-refractory: 120 mg QD in combination with a 0.1 mg diethylstilbestrol tablet.

4)Endometrial carcinoma, palliative treatment of advanced disease (recurrent, inoperable, or metastatic): 40-320 mg/day in divided doses.

PEDIATRIC

Safety and effectiveness not established in pediatric patients.

Contraindication

1)History of hypersensitivity to megestrol acetate or any component of the formulation.

2)Known or suspected pregnancy.

Precaution
 
Adverse reaction

Hypertension, cardiomyopathy, chest pain, edema, palpitation, peripheral edema, heart failure; headache, insomnia, fever, pain, abnormal thinking, confusion, depression, hypoesthesia, seizure, mood changes, malaise, lethargy; rash, alopecia, pruritus, vesiculobullous rash; hyperglycemia, gynecomastia, adrenal insufficiency, amenorrhea, breakthrough bleeding, cervical erosion and secretions (changes), breast tenderness increased, cushing's syndrome, diabetes, glucose intolerance, HPA axis suppression, hot flashes, hypercalcemia, menstrual flow changes, spotting, vaginal bleeding pattern changes; diarrhea, flatulence, vomiting, nausea, dyspepsia, abdominal pain, constipation, salivation increased, xerostomia, weight gain (not attributed to edema or fluid retention); impotence, decreased libido, urinary incontinence, urinary tract infection, urinary frequency ; anemia, leucopenia; hepatomegaly, LDH increased, cholestatic jaundice, hepatotoxicity; weakness, neuropathy, paresthesia, carpal tunnel syndrome; amblyopia; albuminuria; dyspnea, cough, pharyngitis, pneumonia, hyperpnea; diaphoresis, herpes infection, infection, moniliasis, tumor flare; thromboembolic phenomena (including deep vein thrombosis, pulmonary embolism, thrombophlebitis).

Drug Interaction
 
Pregnancy Category
Megestrol                                                 

點小圖看大圖

現行藥物外觀

中文名:麥格斯口服懸液劑 40 毫克/毫升

廠牌:晟德/台灣東洋

 

 

Product name
Megest
Dosage form
(40mg/ml,120ml)口服懸液
Indications
 
Administration & Dosage

PO

ADULT

1)Breast cancer, palliative treatment of advanced disease (recurrent, inoperable, or metastatic): 40 mg QID.

2)Cachexia associated with AIDS: initial, 800 mg/day; maintenance, 400 and 800 mg/day were found to be clinically effective.

3)Carcinoma of prostate, Advanced hormone-refractory: 120 mg QD in combination with a 0.1 mg diethylstilbestrol tablet.

4)Endometrial carcinoma, palliative treatment of advanced disease (recurrent, inoperable, or metastatic): 40-320 mg/day in divided doses.

PEDIATRIC

Safety and effectiveness not established in pediatric patients.

Contraindication

1)History of hypersensitivity to megestrol acetate or any component of the formulation.

2)Known or suspected pregnancy.

Precaution
 
Adverse reaction

Hypertension, cardiomyopathy, chest pain, edema, palpitation, peripheral edema, heart failure; headache, insomnia, fever, pain, abnormal thinking, confusion, depression, hypoesthesia, seizure, mood changes, malaise, lethargy; rash, alopecia, pruritus, vesiculobullous rash; hyperglycemia, gynecomastia, adrenal insufficiency, amenorrhea, breakthrough bleeding, cervical erosion and secretions (changes), breast tenderness increased, cushing's syndrome, diabetes, glucose intolerance, HPA axis suppression, hot flashes, hypercalcemia, menstrual flow changes, spotting, vaginal bleeding pattern changes; diarrhea, flatulence, vomiting, nausea, dyspepsia, abdominal pain, constipation, salivation increased, xerostomia, weight gain (not attributed to edema or fluid retention); impotence, decreased libido, urinary incontinence, urinary tract infection, urinary frequency ; anemia, leucopenia; hepatomegaly, LDH increased, cholestatic jaundice, hepatotoxicity; weakness, neuropathy, paresthesia, carpal tunnel syndrome; amblyopia; albuminuria; dyspnea, cough, pharyngitis, pneumonia, hyperpnea; diaphoresis, herpes infection, infection, moniliasis, tumor flare; thromboembolic phenomena (including deep vein thrombosis, pulmonary embolism, thrombophlebitis).

Drug Interaction
 
Pregnancy Category

X

Notes
 
最近更新日期 2015年9月24日