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 Pyrazinamide 　　　仿單連結　　　　　　　　　　　　　　　　　　　　　　　　　　　　

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 21P051pyrazinamide 500mg/Tab.現行藥物外觀

中文名:比井羧胺錠

廠牌:培力

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 21P051pyrazinamide 500mg/Tab.

中文名:邁得

廠牌:溫士頓
Product name
 mide / Pyrazinamide / PZA
Dosage form
 21P051, 500mg/Tab.
Indications
Tuberculosis, in combination with other antitubercular drugs
Administration & Dosage

PO,
Adult & Pediatric
Tuberculosis, in combination with other antitubercular drugs: 15-30 mg/kg QD; or 50-70 mg/kg 2-3 times/wk, depending on the treatment regimen.
Max. Adult, 2 g/d; 3 g/dose for the 3 times/wk regimen, 4 g/dose for the 2 times/wk regimen. Children, 2 g/d, 3 g/dose for the 3 times/wk regimen, 4 g/dose for the 2 times/wk regimen.
Contraindication

acute gout;hypersensitivity to pyrazinamide products;severe hepatic dysfunction.
Precaution
 
Adverse reaction
 M: Arthralgia (related to hyperuricemia; usually mild and self-limiting) R: Gouty arthritis; hepatotoxicity (related to large doses; i.e. 40 to 50 mg /kg/d for prolonged periods of time); itching; skin rash
Drug Interaction
 
Pregnancy Category
 C
Notes
The usual dose of pyrazinamide for persons infected with HIV is 20- 30 mg/kg/d for the first 2 mo of therapy. 
最近更新日期 2015年9月24日