IM, IV infusion
Adult
Usual dose: 1-1.7 mg/kg q8h for
7-10 days or more.
Uncomplicated UTI:
<
60 kg
, 3 mg/kg QD or 1.5 mg/kg q12h;
≥
60
kg
, 160 mg QD or 80 mg q12h.
Intralumbar or intraventricular:
4-8 mg QD.
Pediatric
Usual dose:
Premature or full-term neonates<
1wk, 2.5 mg/kg q12-24h for 7-10 days or more.
Older neonates and infants, 2.5
mg/kg q8h-16h for 7-10 days or more.
Children, 2-2.5 mg/kg q8h for 7-10
days or more.
Intralumbar or intraventricular:
Infants and children≥ 3 mo, 1-2 mg QD.
Doses up to 8 mg/d have been used in infants with functioning ventricular
shunts.
Max. Adult, 8
mg/kg/d, in severe, life-threatening infections. |