M or L: Hypertension (4%), hypotension (2%), cardiac failure, cerebrovascular accident, syncope, transient ischemic attack; dizziness (5% to 7%), confusion (6%), headache (6%), anxiety (4%), depression (3%), hallucinations (3%), pain (3%), somnolence (3%), fatigue (2%), aggressive reaction (1% to 2%), ataxia, vertigo; rash; constipation (3% to 5%), diarrhea (5%), weight gain (3%), vomiting (2% to 3%), abdominal pain (2%), weight loss; urinary incontinence (2%), micturition; anemia; alkaline phosphatase increased; back pain (3%), hypokinesia; cataract, conjunctivitis; cough (4%), dyspnea (2%), pneumonia; influenza (4%).
R: Agranulocytosis, pancytopenia, thrombocytopenia, leucopenia;
allergic reaction; angina; gastroenteritis, gastrointestinal hemorrhage, pancreatitis, dysphagia, anorexia, ileus, cholelithiasis, colitis; suicidal ideation, suicide attempt, psychosis, paranoid reaction, loss of consciousness, gait disturbance, delirium, emotional lability, encephalopathy, apathy, aphasia; aspiration pneumonia, pulmonary edema, pulmonary embolism, apnea; arthralgia; torsade de pointes, supraventricular tardive dyskinesia, QT prolongation, orthostatic hypotension, MI, atrial fibrillation, tachycardia, bradycardia, cardiac arrest, AV block; retinal detachment, retinal hemorrhage, myopia, macula lutea degeneration, glaucoma, diplopia, conjunctival hemorrhage, corneal opacity, blurred vision; INR increased, DVT, cerebral hemorrhage, cerebral infarction; hyper/hypoglycemia, hyperlipidemia, hyponatremia, diabetes mellitus aggravated; extrapyramidal disorder; urinary retention, renal failure, hematuria, dysuria; fever; tinnitus, hearing decreased; neuralgia, neuropathy, hemiplegia; hepatic failure, hepatitis; NMS; urticaria, Stevens-Johnson syndrome, pruritus, paresthesia; parkinsonism; peripheral edema; seizure; sepsis; thrombotic thrombocytopenic purpura |
