I&D: IM,
Adult
Percutaneous or permucosal exposure to hepatitis B:
For unvaccinated patients: 0.06 ml/kg followed by initiation of the hepatitis B virus vaccine recombinant vaccination series.
For vaccinated patients: if tests reveal< 10 mIU/ml of anti-HBs activity, 0.06 ml/kg in addition to a hepatitis B virus vaccine recombinant booster dose.
Sexual exposure to hepatitis B: 0.06 ml/kg followed by initiation of the hepatitis B virus vaccine recombinant vaccination series within 14 days of the last sexual contact or if sexual contact with the infected person will continue.
Pediatric
Perinatal exposure to hepatitis B:
For infants of HBsAg(+) mothers, 0.5 ml within the first 12 hr after birth.
For infants of mothers not screened for HBsAg, 0.5 ml as soon as possible and within the first 7 days after birth if the mother is found to be HBsAg(+).
Household exposure to hepatitis B:
Infants less than 12 mo of age, IM, 0.5 ml. |
